It s well known that a proper oral hygiene is essential for healthy teeth and gums and has a positive impact on people health and social life. This includes daily brushing and flossing.

This Belgian company has already a panoply of solutions in its portforlio of dedicated products but would like to bring to its customers breakthrough cleaning benefits with daily use safety profile. They would like to identify safe and effective removal of food and debris between teeth via chemical approach that would increase compliance and enhance the oral health benefits driven by the flossing action, without having to floss. They are exploring alternatives to flossing.

The Belgian company is therefore looking for collaboration with industrial partners able to provide the expected solutions.

The kind of expected collaboration is a commercial agreement with technical assistance or a licence agreement allowing the large account envisage discussions on the terms of the licence use.
Advantages and innovation
Technical Specification or Expertise Sought
The company is looking for:

• Compounds or devices that:
- Removes dental calculus with home hygiene tools (ideally regular brushing) in a useable time frame, minimally noticeable on buccal and lingual anterior tooth surfaces, ideally all surfaces
- Minimizes the deposition, growth or maturation of plaque, ideally without mechanical removal forces
- Enables dispersion of biofilm on hard and/or all soft tissues, in particular tongue
- Are able to provide long lasting and noticeable clean feel benefits over an extended period
- Chemically remove/lift debris and/or plaque from in between teeth or from below the gum

• Product/technology FORM may include:
- Paste/gel
- Rinse
- Device/alternate forms/combination

• Preference for products/technologies that:

- Performance and efficacy is demonstrated in recognized oral care performance tests
- Data available on full formulations
- Human safety has been confirmed and material(s) are GRAS (Generally Recognized As Safe) such as food grade ingredients, CONEG (Coalition of Northeastern Governors ) and PROP65 (Proposition 65) compliant
- Have consumer or clinical studies, FDA (Food and Drug Administration) approval under the appropriate class, or an expedited path to FDA approval for US markets. It will consider global rest of world relevant technologies – will require understanding of regulatory path
- Have granted or filed patent applications
- Provides a signal tied to cleaning (e.g. sensorial, healthy color, etc.)
- Products provide additional benefits (e.g. fresh breath, clean feel) ideally over a prolonged period of time

The company is NOT interested in:
• Technologies/products that need to be applied by dental professionals or require a prescription
• Technologies/products that require extensive laboratory, safety, regulatory or clinical development