Title
Looking for enhanced delivery of oral care actives and flavors
AbstractA Belgian multinational active in the consumer goods wishes to improve the performance and consumer experience of oral care products using formulation excipients to improve deposition, retention and protection of actives, flavors and sensates for extended periods. Industrial partners are sought for commercial agreement with technical assistance or for licence agreement.
DescriptionA Belgian multinational active in the consumer goods wishes to improve the performance and the consumer experience of oral care products using new formulation excipients. With such an aim, this company is looking for oral care products whose formulation excipients improve deposition, retention and protection of actives, flavors and sensates for extended periods.
Advantages and innovation
Technical Specification or Expertise Sought
Products technologies or ingredients are expected to have the following benefit areas of interest :
1) Hard tissue:
- Improved delivery of monograph actives resulting in superior anti-cavity and/or increased reduction in dental hypersensitivity
- Delivery and retention of materials onto the enamel surface to deliver a long lasting barrier against acid erosion
- Delivery and retention of materials into the biofilm/plaque matrix for limiting enamel demineralizing challenges and enhancing remineralization and lesion repair
2) Gum Health
- Increased delivery of stannous fluoride and/or CPC or other monograph actives that translates to increased reduction in plaque, plaque toxicity, and gingivitis
3) Experiential Elements
-Long lasting mouth retention technology that delivers flavors and sensates on soft tissues for 4+ hours or a change in hard tissue contact anel
- Ideal delivery technology will also provide lubricity and slick mouth feel
Preferred product forms include:
- Paste,
- Rinse,
- Gels;
However other forms will be considered
The company has a preference for technologies where:
- Technology deposits, retains and releases materials from both hard and/or soft tissues
- Performance, stability and compatibility data has been shown in full oral care formulations that are aqueous based. By performance, the company means changes in salivary pK profiles, uptake in or on target surfaces vs standard technologies
- Unique capability exists to demonstrate and quantify the benefit
- Performance data exists (technical / consumer / clinical) versus appropriate negative controls
- Human safety has been confirmed or material is GRAS (Generally Recognized As Safe)
Granted or filed patent applications are preferred
The company is NOT interested in:
- Technologies that require extensive clinical development