Interstitial fluid (ISF), the fluid in spaces between the cells, is a novel source of biomarkers that compliments conventional sources like blood and urine.
The use of ISF for therapeutic drug monitoring, dermatological diagnoses and continuous biomarker measurements provides unique information and is potentially pain-free. Despite the advantages, ISF has received limited attention due to the lack of simple collection methods.

Thus, there is a need for a simple ISF collection method.

This company is looking for these technolgies so as to provide its customers with more effective products and enhanced experiences while using those products.
Advantages and innovation
Technical Specification or Expertise Sought
The company would like to access interstitial fluid solution to advance discovery of novel biomarkers related to skin health and whole-body health and enable them to use ISF for monitoring delivery/bioavailability of actives and sensing and demoing product efficacy (first use benefit).

With such a purpose, the company is looking for technologies sampling the interstitial fluid in skin which are:

- Minimally invasive – No hypodermic needles or large instrumentation needed.
- Simple – Allow for simple, point-of-care collection of ISF.
- Quick – Collection can be done within minutes in clinic or at home.
- Clean – Blood-free
- Compliant – Safety and regulatory clearance for use
- Flexible – Easy to be integrated with microfluidic, lateral flow, or electrochemical device.

The company is NOT looking for:

• Tape strips, swabs, and other techniques that only sample stratum corneum.
• Invasive techniques that involve blood.